Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3708818 | 0.99 | MAPT (0.58) | MAPTHTR1ASLC6A4ALDH1A1GAA | |
| SCHEMBL2769304 | 0.89 | ADRA1D (0.62) | HTR1AALDH1A1ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL3709653 | 0.86 | ADRA1D (0.55) | MAPTADRA1DADRA1AADRA1B | |
| SCHEMBL3711300 | 0.84 | MAPT (0.70) | MAPTALDH1A1ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL3706215 | 0.83 | MAPT (0.68) | MAPTALDH1A1ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL3703905 | 0.78 | MEN1 (0.61) | MAPTALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL3708962 | 0.78 | MAPT (0.61) | MAPTHTR1AALDH1A1ADRA1DADRA1A | |
| SCHEMBL3707936 | 0.78 | MAPT (0.51) | MAPTADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL3707739 | 0.77 | MAPT (0.60) | MAPTALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL3713043 | 0.77 | CHRM2 (0.47) | HTR1AALDH1A1ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |