SCHEMBL3709290

SCHEMBL3709290

C[SiH](C)C1(CCCCNCCN)CCCCO1

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.31
CA2 P00918 2/20 0.31
CA4 P22748 2/20 0.31
CA6 P23280 2/20 0.31
CA5A P35218 2/20 0.31
CA7 P43166 2/20 0.31
CA9 Q16790 2/20 0.31
CA14 Q9ULX7 2/20 0.31
CA5B Q9Y2D0 2/20 0.31
CA3 P07451 1/20 0.31
MEN1 O00255 1/20 0.31
F13A1 P00488 1/20 0.31
CYP1A2 P05177 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP2C19 P33261 1/20 0.31
THPO P40225 1/20 0.31
CASP2 P42575 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5693369 0.95 CA12 (0.32) CA12CA2CA4CA6CA5A
SCHEMBL7916836 0.86
SCHEMBL6933322 0.84
SCHEMBL28939437 0.78 SCN2A (0.31)
SCHEMBL7134159 0.78
SCHEMBL29185348 0.77
SCHEMBL28451905 0.76
SCHEMBL2465421 0.76 SCN2A (0.33)
SCHEMBL28807732 0.76 SCN2A (0.33)
SCHEMBL28330778 0.76 SCN2A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3450532-B1 USE OF AN AMODIMETHICONE/ORGANOSILICON-CONTAINING COPOLYMER, DETERGENT, USE OF THE DETERGENT AND WASHING METHOD HENKEL AG & CO KGAA (DE) 2022-05-04 EP claimed
EP-2207904-B1 COATED LEATHER LANXESS DEUTSCHLAND GMBH (DE) 2014-02-12 EP claimed
EP-2207904-A2 COATED LEATHER Schaefer, Philipp (DE) 2010-07-21 EP claimed
WO-2009049728-A2 COATED LEATHER SCHAEFER PHILIPP (DE) 2009-04-23 WO claimed
EP-3450532-B1 USE OF AN AMODIMETHICONE/ORGANOSILICON-CONTAINING COPOLYMER, DETERGENT, USE OF THE DETERGENT AND WASHING METHOD HENKEL AG & CO KGAA (DE) 2022-05-04 EP disclosed
EP-2711438-B1 Coated leather LANXESS DEUTSCHLAND GMBH (DE) 2020-11-11 EP disclosed
US-10543156-B2 Shaping keratin fibres using 2-oxazolidinone compounds THE PROCTER & GAMBLE COMPANY (US) 2020-01-28 US disclosed
EP-3256096-B1 SHAPING KERATIN FIBRES USING ARABINOSE AND ETHYLENE CARBONATE PROCTER & GAMBLE (US) 2019-04-17 EP disclosed
US-10064799-B2 Shaping keratin fibres using carbonate ester THE PROCTER & GAMBLE COMPANY (US) 2018-09-04 US disclosed
EP-3310329-A1 SHAPING KERATIN FIBRES USING 2-OXAZOLIDINONE COMPOUNDS The Procter and Gamble Company (US) 2018-04-25 EP disclosed
EP-3310325-A1 SHAPING KERATIN FIBRES USING DIALDEHYDE COMPOUNDS The Procter and Gamble Company (US) 2018-04-25 EP disclosed
EP-3297731-A1 SHAPING KERATIN FIBRES USING ARABINOSE AND ETHYLENE CARBONATE The Procter and Gamble Company (US) 2018-03-28 EP disclosed
WO-2015094760-A1 SHAPING KERATIN FIBRES USING CARBONATE ESTER THE PROCTER & GAMBLE COMPANY (US) 2015-06-25 WO disclosed
US-20150174037-A1 SHAPING KERATIN FIBRES USING CARBONATE ESTER THE PROCTER & GAMBLE COMPANY 2015-06-25 US disclosed
EP-2711438-A2 Coated leather LANXESS Deutschland GmbH (DE) 2014-03-26 EP disclosed
EP-2207904-B1 COATED LEATHER LANXESS DEUTSCHLAND GMBH (DE) 2014-02-12 EP disclosed
EP-2105454-B1 Thioether functionalised organopolysiloxanes SCHILL & SEILACHER STRUKTOL GMBH (DE) 2012-09-12 EP disclosed
EP-2207904-A2 COATED LEATHER Schaefer, Philipp (DE) 2010-07-21 EP disclosed
EP-2105454-A1 Thioether functionalised organopolysiloxanes Schill + Seilacher "Struktol" Aktiengesellschaft (DE) 2009-09-30 EP disclosed
WO-2009049728-A2 COATED LEATHER SCHAEFER PHILIPP (DE) 2009-04-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10543156-B2 Shaping keratin fibres using 2-oxazolidinone compounds KRT18, COL14A1, KIF5B CA12 3449/4885CA2 3088/4885CA4 2547/4885
US-10064799-B2 Shaping keratin fibres using carbonate ester KRT18, CKAP4, COL14A1 CA12 206/4885CA2 237/4885CA4 126/4885
US-20150174037-A1 SHAPING KERATIN FIBRES USING CARBONATE ESTER KRT18, CKAP4, COL14A1 CA12 202/4885CA2 235/4885CA4 128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.