KIF5B — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL535127	0.50	10/20
SCHEMBL637027	0.48	10/20
SCHEMBL8684	0.66	9/20
Hydrochloric Acid (SCHEMBL907165)	0.62	9/20
SCHEMBL216888	0.50	9/20
SCHEMBL535258	0.50	9/20
SCHEMBL666884	0.49	9/20
SCHEMBL296984	0.49	8/20
SCHEMBL1442511	0.69	7/20
SCHEMBL1442513	0.69	7/20
SCHEMBL1444001	0.69	7/20
SCHEMBL1444002	0.69	7/20
SCHEMBL1441566	0.66	7/20
SCHEMBL1441569	0.66	7/20
SCHEMBL1441871	0.58	7/20
SCHEMBL1441873	0.58	7/20
SCHEMBL1444354	0.58	7/20
Trifluoroacetic Acid (SCHEMBL907135)	0.55	7/20
SCHEMBL535303	0.53	7/20
SCHEMBL1807327	0.53	7/20

Clinical trials — most relevant to KIF5B by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Dimethyl Fumarate in Adrenomyeloneuropathy	PHASE2/PHASE3	ACTIVE_NOT_RECRUITING
Study of ABT-751 in Patients With Refractory Hematologic Malignancies	PHASE1	COMPLETED
Far Infrared Irradiation for the Management, Control and Treatment of Frontotemporal Dementia	PHASE1	UNKNOWN
Transcutaneous Functional Magnetic Muscle Stimulation in Critically Ill	nan	UNKNOWN
Spastic Paraplegia - Centers of Excellence Research Network	nan	RECRUITING
Biomarker Research in Inherited Movement Disorders	nan	RECRUITING
Peripheral Neurofilament Levels and Amyotrophic Lateral Sclerosis	nan	COMPLETED
Progressive Familial Intrahepatic Cholestasis in Indian Children - Establishing an Indian PFIC Registry	nan	UNKNOWN
Genetic Study of Patients With Primary Ciliary Dyskinesia	nan	COMPLETED
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy	nan	COMPLETED
Muscle Tissue Bank for Muscular Dystrophy	nan	COMPLETED
Diagnostic of Chemotherapy Induced Neuropathy in Children	nan	COMPLETED
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others	nan	RECRUITING
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)	nan	RECRUITING
CoMPaSS-NMD - Computational Models for New Patients Stratification Strategies of HNMD	nan	ENROLLING_BY_INVITATION
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
Molecular and Genetic Studies of Congenital Myopathies	nan	RECRUITING
Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development	nan	COMPLETED
Gait in Rare Diseases	nan	COMPLETED
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases	nan	COMPLETED
Autologous Stem/Stromal Cells in Neurological Disorders and Disease	nan	UNKNOWN
Biomarkers and Validation of Selected Outcome Measures (CMTBiomarker)	nan	COMPLETED
Mapping Disease Pathways for Biliary Atresia	nan	RECRUITING
Clinical Importance of Carrier Status of Recessive Gene Mutations in Myopathy (CICS)	nan	UNKNOWN
Pediatric Evaluation and Registry for Liver Cholestasis in Canada	nan	RECRUITING
Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS)	nan	COMPLETED
Core Stability Exercises and Hereditary Ataxia	nan	COMPLETED
Early Detection and Characterization of Primary Ciliary Dyskinesia	nan	UNKNOWN
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome	nan	RECRUITING
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a KIF5B binder may also engage these)

Protein	Name	Similarity
Q2PQA9	—	1.000	Q2PQA9 →
P56536	—	1.000	P56536 →
P28738	—	1.000	P28738 →
P21613	—	1.000	P21613 →
KIF5C	Kinesin heavy chain isoform 5C	1.000	landscape →
P35978	—	1.000	P35978 →
P17210	—	1.000	P17210 →
P34540	—	1.000	P34540 →
Q61768	—	1.000	Q61768 →
Q91785	—	1.000	Q91785 →
KIF15	Kinesin-like protein KIF15	1.000	landscape →
Q5R9K7	—	1.000	Q5R9K7 →
KIF5A	Kinesin heavy chain isoform 5A	1.000	landscape →
Q7Z4S6	—	0.999	Q7Z4S6 →
Q90640	—	0.999	Q90640 →
Q498L9	—	0.999	Q498L9 →
Q8GS71	—	0.999	Q8GS71 →
O35066	—	0.999	O35066 →
A8WVU9	—	0.998	A8WVU9 →
F4IIS5	—	0.998	F4IIS5 →
O23826	—	0.998	O23826 →
Q6QLM7	—	0.998	Q6QLM7 →
Q9QXL2	—	0.998	Q9QXL2 →
F4IJK6	—	0.998	F4IJK6 →
Q9GYZ0	—	0.998	Q9GYZ0 →
P46867	—	0.998	P46867 →
P33175	—	0.998	P33175 →
P46863	—	0.998	P46863 →
Q9AWM8	—	0.997	Q9AWM8 →
Q86Z98	—	0.997	Q86Z98 →