Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 4/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709525 | 1.00 | HCAR2 (0.63) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL3713054 | 0.94 | ATM (0.55) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL3713051 | 0.94 | ATM (0.55) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL652270 | 0.88 | TSHR (0.62) | HCAR2ATMNAAAHPGDTSHR | |
| SCHEMBL3714010 | 0.87 | ATM (0.58) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL9747274 | 0.87 | HCAR2 (0.67) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL3713298 | 0.87 | HCAR2 (0.67) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL3714013 | 0.87 | ATM (0.58) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL9006147 | 0.87 | HCAR2 (0.67) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL27857610 | 0.87 | HCAR2 (0.67) | HCAR2ATMMAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398874-B1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | LUBRIZOL CORP (US) | 2017-04-26 | — | — | EP | disclosed |
| EP-2398874-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | The Lubrizol Corporation (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010096291-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | THE LUBRIZOL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |