Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714010 | 1.00 | ATM (0.58) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL3713054 | 0.93 | ATM (0.55) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL3713051 | 0.93 | ATM (0.55) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL652535 | 0.87 | TSHR (0.61) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL3709526 | 0.87 | HCAR2 (0.63) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL3709525 | 0.87 | HCAR2 (0.63) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL25341851 | 0.82 | ALDH1A1 (0.55) | ATMRAB9ATSHRTDP1CA1 | |
| SCHEMBL10837363 | 0.79 | ATM (0.62) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL27510969 | 0.79 | ATM (0.74) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL23468886 | 0.78 | TSHR (0.63) | ATMHCAR2TSHRTDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398874-B1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | LUBRIZOL CORP (US) | 2017-04-26 | — | — | EP | disclosed |
| EP-2398874-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | The Lubrizol Corporation (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010096291-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | THE LUBRIZOL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |