Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.61 |
| ▸ | DRD4 | P21917 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3710452 | 0.99 | DRD2 (0.59) | DRD2DRD4DRD3SMN1; SMN2RECQL | |
| SCHEMBL3709570 | 0.86 | SMN1; SMN2 (0.59) | DRD2DRD4DRD3SMN1; SMN2RECQL | |
| Hydrochloric Acid SCHEMBL3706389 | 0.85 | SMN1; SMN2 (0.57) | DRD2DRD4DRD3SMN1; SMN2RECQL | |
| SCHEMBL6864941 | 0.85 | DRD4 (0.81) | DRD2DRD4DRD3ALDH1A1KDM4E | |
| SCHEMBL3709310 | 0.85 | RECQL (0.70) | DRD2DRD4DRD3SMN1; SMN2RECQL | |
| SCHEMBL3712719 | 0.84 | MAPT (0.74) | DRD2DRD4DRD3SMN1; SMN2RECQL | |
| Hydrochloric Acid SCHEMBL3706762 | 0.83 | RECQL (0.68) | DRD2DRD4DRD3SMN1; SMN2RECQL | |
| SCHEMBL3563737 | 0.83 | KDM4E (0.64) | DRD2DRD4DRD3ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL3706847 | 0.82 | MAPT (0.72) | DRD2DRD4DRD3SMN1; SMN2RECQL | |
| Hydrochloric Acid SCHEMBL3710903 | 0.82 | KDM4E (0.62) | DRD2DRD4DRD3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | claimed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |