Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.76 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.61 |
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.51 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2112042 | 0.86 | PKM (1.00) | PKMPTGDR2POLBSMN1; SMN2PTGDR | |
| SCHEMBL23949850 | 0.85 | PKM (0.55) | PKMFFAR1FFAR4PTGDR2AKR1A1 | |
| SCHEMBL30353364 | 0.85 | PKM (0.55) | PKMFFAR1FFAR4PTGDR2AKR1A1 | |
| SCHEMBL18045699 | 0.84 | PKM (0.72) | PKMFFAR1FFAR4PTGDR2POLB | |
| SCHEMBL4517198 | 0.82 | PKM (0.53) | PKMFFAR1FFAR4SMN1; SMN2 | |
| SCHEMBL31472051 | 0.82 | FFAR4 (0.64) | PKMFFAR1FFAR4SCD | |
| SCHEMBL4374302 | 0.80 | PKM (0.62) | PKMFFAR1FFAR4PTGDR2AKR1A1 | |
| SCHEMBL4384639 | 0.79 | PKM (0.61) | PKMFFAR1FFAR4PTGDR2POLB | |
| SCHEMBL4138843 | 0.79 | PKM (0.71) | PKMPTGDR2AKR1A1AKR1B1POLB | |
| SCHEMBL31468805 | 0.79 | PKM (0.61) | PKMFFAR4PTGDR2AKR1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396295-A1 | PHENOXY ACETIC ACID DERIVATIVES | Merck Serono S.A. (CH) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010092043-A1 | PHENOXY ACETIC ACID DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-08-19 | — | — | WO | disclosed |