SCHEMBL3709900

SCHEMBL3709900

COc1cccc2c1CCCC2CNC1CC1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 1/20 0.56
SIGMAR1 Q99720 7/20 0.54
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17257949 1.00 KDM4C (0.56) KDM4CSIGMAR1CA1CA2
Hydrochloric Acid SCHEMBL9326664 0.85 SIGMAR1 (0.55) KDM4CSIGMAR1CA1CA2
Hydrochloric Acid SCHEMBL8815857 0.85 SIGMAR1 (0.55) KDM4CSIGMAR1CA1CA2
Hydrochloric Acid SCHEMBL9521770 0.83 SIGMAR1 (0.56) KDM4CSIGMAR1
SCHEMBL9520305 0.82 SIGMAR1 (0.55) KDM4CSIGMAR1CA1CA2
SCHEMBL15839894 0.80 SIGMAR1 (0.57) SIGMAR1CA1CA2
SCHEMBL8019430 0.80 SIGMAR1 (0.57) SIGMAR1
SCHEMBL8811492 0.80 SIGMAR1 (0.57) SIGMAR1
SCHEMBL9549201 0.80 SIGMAR1 (0.57) SIGMAR1CA1CA2
SCHEMBL15286771 0.80 SIGMAR1 (0.57) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9686985-B2 Fungicide N-cycloalkyl-N-bicyclicmethylene-carboxamide derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-06-27 US claimed
US-20160366885-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH 2016-12-22 US claimed
US-9233929-B2 Fungicide N-cycloalkyl-N-bicyclimethylene-carboxamide derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-01-12 US claimed
US-20150327548-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-11-19 US claimed
EP-2831048-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES Bayer Intellectual Property GmbH (DE) 2015-02-04 EP claimed
WO-2013144086-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-10-03 WO claimed
US-20130102790-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLIMETHYLENE-CARBOXAMIDE DERIVATIVES BAYER CROPSCIENCE AG 2013-04-25 US claimed
EP-2391608-B1 FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2013-03-06 EP claimed
EP-2391608-A1 Fungicide n-cycloalkyl-n-bicyclicmethylene-carboxamide derivatives Bayer CropScience AG (DE) 2011-12-07 EP claimed
US-20110294863-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLIMETHYLENE-CARBOXAMIDE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2011-12-01 US claimed
WO-2010086311-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2010-08-05 WO claimed
US-9686985-B2 Fungicide N-cycloalkyl-N-bicyclicmethylene-carboxamide derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-06-27 US disclosed
EP-2831048-B1 FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES BAYER IP GMBH (DE) 2017-04-26 EP disclosed
US-20160366885-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH 2016-12-22 US disclosed
US-9468211-B2 Fungicide N-cycloalkyl-N-bicyclicmethylene-carboxamide derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-10-18 US disclosed
EP-2391608-B1 FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2013-03-06 EP disclosed
US-8349884-B2 Fungicide N-cycloalkyl-N-bicyclimethylene-carboxamide derivatives BAYER CROPSCIENCE AG (DE) 2013-01-08 US disclosed
EP-2391608-A1 Fungicide n-cycloalkyl-n-bicyclicmethylene-carboxamide derivatives Bayer CropScience AG (DE) 2011-12-07 EP disclosed
US-20110294863-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLIMETHYLENE-CARBOXAMIDE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2011-12-01 US disclosed
WO-2010086311-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2010-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160366885-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES CBR3, CNPY2, CYP51A1 KDM4C 362/4885SIGMAR1 3236/4885CA1 2140/4885
US-20150327548-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLICMETHYLENE-CARBOXAMIDE DERIVATIVES CBR3, CNPY2, CYP51A1 KDM4C 362/4885SIGMAR1 3236/4885CA1 2140/4885
US-20110294863-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLIMETHYLENE-CARBOXAMIDE DERIVATIVES CBR3, CBR1, CNPY2 KDM4C 580/4885SIGMAR1 2118/4885CA1 1147/4885
US-20130102790-A1 FUNGICIDE N-CYCLOALKYL-N-BICYCLIMETHYLENE-CARBOXAMIDE DERIVATIVES CBR3, CBR1, CNPY2 KDM4C 727/4885SIGMAR1 1739/4885CA1 1157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.