SCHEMBL3710150

SCHEMBL3710150

COc1ccc(C(N)CC2(OS(C)(=O)=O)CCCCC2)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 6/20 0.45
SLC6A3 Q01959 6/20 0.45
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
SLC6A2 P23975 5/20 0.40
LMNA P02545 1/20 0.40
CNR1 P21554 1/20 0.40
HTR2A P28223 1/20 0.40
HRH1 P35367 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
ACHE P22303 1/20 0.37
CTSK P43235 1/20 0.36
KMT2A Q03164 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3801391 0.81 CYP1A2 (0.47) SLC6A4SLC6A3CYP1A2CYP2D6CYP2C19
SCHEMBL3347205 0.75 SLC6A4 (0.51) SLC6A4SLC6A3CYP1A2CYP2D6CYP2C19
SCHEMBL8038690 0.75 SLC6A4 (0.51) SLC6A4SLC6A3CYP1A2CYP2D6CYP2C19
SCHEMBL3710148 0.74 SLC6A4 (0.45) SLC6A4SLC6A3SLC6A2LMNACNR1
Hydrochloric Acid SCHEMBL3930855 0.74 SLC6A4 (0.52) SLC6A4SLC6A3CYP1A2CYP2D6CYP2C19
Acetic Acid SCHEMBL5795551 0.73 SLC6A4 (0.46) SLC6A4SLC6A3CYP1A2CYP2D6CYP2C19
SCHEMBL21115782 0.70 CYP1A2 (0.56) SLC6A4CYP1A2CYP2D6CYP2C19CA1
SCHEMBL6327230 0.64 SLC6A4 (0.44) SLC6A4SLC6A3CYP1A2CYP2D6CYP2C19
SCHEMBL4963046 0.63 CYP1A2 (0.66) SLC6A4CYP1A2CYP2D6CYP2C19CA1
SCHEMBL4197005 0.63 CYP1A2 (0.66) SLC6A4SLC6A3CYP1A2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010100520-A1 A PROCESS FOR PREPARATION OF PHENETHYLAMINE DERIVATIVE HIKAL LIMITED (IN) 2010-09-10 WO claimed
WO-2010100520-A1 A PROCESS FOR PREPARATION OF PHENETHYLAMINE DERIVATIVE HIKAL LIMITED (IN) 2010-09-10 WO disclosed