Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347205 | 1.00 | SLC6A4 (0.51) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| Hydrochloric Acid SCHEMBL3930855 | 0.98 | SLC6A4 (0.52) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| Acetic Acid SCHEMBL5795551 | 0.93 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL3709825 | 0.85 | NQO1 (0.40) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL6328367 | 0.83 | SLC6A2 (0.51) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL4618228 | 0.81 | SLC6A2 (0.45) | SLC6A4SLC6A3SLC6A2LMNACYP1A2 | |
| SCHEMBL4625904 | 0.80 | MME (0.36) | SLC6A4SLC6A3SLC6A2HTR2A | |
| SCHEMBL4967524 | 0.79 | SLC6A2 (0.56) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL8040630 | 0.79 | SLC6A4 (0.49) | SLC6A4SLC6A3SLC6A2LMNACNR1 | |
| SCHEMBL8038699 | 0.79 | SLC6A4 (0.49) | SLC6A4SLC6A3SLC6A2LMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044760-A1 | DENDRIMER CONJUGATES OF ANTIDEPRESSANT AND ANTIPSYCHOTIC AGENTS AND THEIR METHODS OF USE | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024044756-A1 | DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY OF PSYCHEDELIC THERAPEUTICS | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2000076956-A2 | ENANTIOMERS OF N-DESMETHYL VENLAFAXINE | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-12-21 | — | — | WO | disclosed |