Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.59 |
| ▸ | HRH1 | P35367 | 11/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713221 | 0.91 | HRH3 (0.60) | HRH3HRH1KCNH2ADRA1BADRA1A | |
| Formic Acid SCHEMBL3710295 | 0.90 | HRH3 (0.70) | HRH3HRH1KCNH2ADRA1BADRA1A | |
| SCHEMBL3720054 | 0.90 | HRH3 (0.72) | HRH3HRH1KCNH2ADRA1BADRA1A | |
| SCHEMBL3712040 | 0.86 | HRH3 (0.42) | HRH3HRH1KCNH2ADRA1BADRA1A | |
| SCHEMBL3709424 | 0.84 | HRH3 (0.54) | HRH3HRH1KCNH2ADRA1BADRA1A | |
| Formic Acid SCHEMBL3714102 | 0.82 | HRH3 (0.61) | HRH3HRH1KCNH2ADRA1BADRA1A | |
| SCHEMBL3717565 | 0.81 | HRH3 (0.54) | HRH3HRH1KCNH2ADRA1BADRA1A | |
| SCHEMBL3708676 | 0.80 | HRH3 (0.67) | HRH3HRH1KCNH2ADRA1BADRA1A | |
| SCHEMBL3711508 | 0.79 | HRH1 (0.64) | HRH3HRH1KCNH2ADRA1BADRA1A | |
| SCHEMBL3711533 | 0.77 | HRH1 (0.74) | HRH3HRH1KCNH2ADRA1BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |