Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 17/20 | 0.55 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715192 | 0.89 | SLC9A1 (0.59) | SLC9A1S1PR2S1PR4 | |
| SCHEMBL3720065 | 0.86 | SLC9A1 (0.55) | SLC9A1KDM4ERAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL3707411 | 0.85 | SLC9A1 (0.54) | SLC9A1S1PR4SMN1; SMN2MAPK1MAPT | |
| SCHEMBL3714112 | 0.84 | SLC9A1 (0.56) | SLC9A1S1PR2S1PR4MAPK1ALDH1A1 | |
| SCHEMBL3719227 | 0.80 | SLC9A1 (0.57) | SLC9A1S1PR2S1PR4 | |
| SCHEMBL3714391 | 0.80 | SLC9A1 (0.53) | SLC9A1S1PR2S1PR4ALDH1A1MAPT | |
| SCHEMBL3710586 | 0.79 | SLC9A1 (0.58) | SLC9A1KDM4ERAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL3719714 | 0.79 | SLC9A1 (0.53) | SLC9A1 | |
| SCHEMBL3712694 | 0.78 | SLC9A1 (0.61) | SLC9A1S1PR2S1PR4MAPK1ALDH1A1 | |
| SCHEMBL3710904 | 0.78 | SLC9A1 (0.56) | SLC9A1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | claimed |
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | disclosed |