Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3702066 | 0.94 | POLB (0.37) | PPARDLPAR1LPAR2LPAR3PTGDR2 | |
| SCHEMBL2337108 | 0.91 | PPARD (0.47) | PPARDLPAR1LPAR2LPAR3PTGDR2 | |
| SCHEMBL3704161 | 0.89 | LPAR1 (0.47) | PPARDLPAR1LPAR2LPAR3 | |
| SCHEMBL3711134 | 0.88 | LPAR1 (0.42) | PPARDLPAR1LPAR2LPAR3 | |
| SCHEMBL3709238 | 0.88 | LPAR1 (0.41) | PPARDLPAR1LPAR2LPAR3PTGDR2 | |
| SCHEMBL2338262 | 0.87 | LPAR1 (0.50) | PPARDLPAR1LPAR2LPAR3 | |
| SCHEMBL3709239 | 0.87 | PPARD (0.46) | PPARDLPAR1LPAR2LPAR3PTGDR2 | |
| SCHEMBL2342065 | 0.85 | PPARD (0.40) | PPARDLPAR1LPAR2LPAR3PTGDR2 | |
| SCHEMBL2335497 | 0.85 | LPAR1 (0.45) | PPARDLPAR1LPAR2LPAR3 | |
| SCHEMBL2336523 | 0.84 | LPAR1 (0.41) | PPARDLPAR1LPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | claimed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |