Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 8/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3705451 | 0.92 | MAPT (0.48) | MAPTKDM4ECYP2C9CYP2C19L3MBTL3 | |
| SCHEMBL3712895 | 0.91 | KDM4E (0.48) | MAPTKDM4ECYP2C9CYP2C19L3MBTL3 | |
| Hydrochloric Acid SCHEMBL3712234 | 0.89 | KDM4E (0.47) | MAPTKDM4ECYP2C9CYP2C19L3MBTL3 | |
| SCHEMBL3715359 | 0.86 | L3MBTL3 (0.55) | MAPTKDM4ECYP2C9CYP2C19L3MBTL3 | |
| Hydrochloric Acid SCHEMBL3705095 | 0.85 | KDM4E (0.54) | MAPTKDM4ECYP2C9CYP2C19L3MBTL3 | |
| SCHEMBL13283841 | 0.83 | CYP2D6 (0.47) | MAPTKDM4ECYP2C9CYP2C19L3MBTL3 | |
| Hydrochloric Acid SCHEMBL3708004 | 0.82 | CYP2D6 (0.46) | MAPTKDM4ECYP2C9CYP2C19L3MBTL3 | |
| SCHEMBL3713534 | 0.81 | CYP2D6 (0.47) | MAPTKDM4ECYP2C9CYP2C19L3MBTL3 | |
| Hydrochloric Acid SCHEMBL3708906 | 0.80 | CYP2D6 (0.46) | MAPTKDM4ECYP2C9CYP2C19L3MBTL3 | |
| SCHEMBL3714821 | 0.80 | MAPT (0.81) | MAPTL3MBTL3MBTD1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | claimed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |