Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.77 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705471 | 0.87 | TRPV1 (0.62) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL3710357 | 0.87 | TRPV1 (0.74) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL14423743 | 0.86 | TRPV1 (1.00) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL3712104 | 0.85 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL13930805 | 0.85 | TRPV1 (0.82) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL6430270 | 0.85 | TRPV1 (0.79) | TRPV1 | |
| SCHEMBL3712605 | 0.84 | TRPV1 (0.56) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL3713787 | 0.84 | PANK3 (0.76) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL6430235 | 0.81 | TRPV1 (0.70) | TRPV1 | |
| SCHEMBL3709637 | 0.81 | KDM4E (0.78) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010092342-A1 | ORGANOSILICON COMPOUNDS AND THEIR USE AS THE MODULATORS OF THE TRPV1 RECEPTOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-19 | — | — | WO | disclosed |