Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 1/20 | 0.76 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433401 | 0.86 | PANK3 (1.00) | PANK3CA12CA1CA2CA9 | |
| SCHEMBL3709346 | 0.85 | PANK3 (0.55) | PANK3CA12CA1CA2CA9 | |
| SCHEMBL3711158 | 0.84 | TRPV1 (0.77) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL3712799 | 0.84 | TRPV1 (0.60) | PANK3CA12CA1CA2CA9 | |
| SCHEMBL3705471 | 0.84 | TRPV1 (0.62) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL3710357 | 0.84 | TRPV1 (0.74) | TRPV1TRPA1KCNH2TRPM8 | |
| SCHEMBL3712104 | 0.82 | TRPV1 (0.80) | CA12CA1CA2CA9TRPV1 | |
| SCHEMBL3712605 | 0.81 | TRPV1 (0.56) | CA12CA1CA2CA9TRPV1 | |
| SCHEMBL13862949 | 0.78 | KDM4E (0.65) | PANK3CA12CA1CA2CA9 | |
| SCHEMBL29678394 | 0.78 | KDM4E (0.65) | PANK3CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010092342-A1 | ORGANOSILICON COMPOUNDS AND THEIR USE AS THE MODULATORS OF THE TRPV1 RECEPTOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-19 | — | — | WO | disclosed |