Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715772 | 0.94 | XDH (0.49) | CDC7DBF4XDHKDM4EALDH1A1 | |
| SCHEMBL3715639 | 0.88 | CDC7 (0.50) | CDC7DBF4XDHKDM4EALDH1A1 | |
| SCHEMBL3710951 | 0.88 | XDH (0.56) | XDHKDM4EALDH1A1THRATHRB | |
| SCHEMBL3706727 | 0.88 | CDC7 (0.46) | CDC7DBF4XDHKDM4EALDH1A1 | |
| SCHEMBL3708174 | 0.87 | CDC7 (0.49) | CDC7DBF4XDHKDM4EALDH1A1 | |
| SCHEMBL3712738 | 0.85 | CDC7 (0.45) | CDC7DBF4XDHKDM4EALDH1A1 | |
| SCHEMBL3713956 | 0.85 | CDC7 (0.51) | CDC7DBF4XDHKDM4EALDH1A1 | |
| SCHEMBL3705195 | 0.84 | CDC7 (0.46) | CDC7DBF4XDHKDM4EALDH1A1 | |
| SCHEMBL3708038 | 0.84 | CDC7 (0.48) | CDC7DBF4ALDH1A1LMNATHRA | |
| SCHEMBL3707161 | 0.83 | CDC7 (0.49) | CDC7DBF4XDHKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| EP-2212333-A1 | THIENOPYRIMIDINE AND PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS | Wyeth LLC (US) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052145-A1 | THIENOPYRIMIDINE AND PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS | WYETH (US) | 2009-04-23 | — | — | WO | disclosed |