SCHEMBL3711795

SCHEMBL3711795

CC(C)[Si](OC[C@H]1C(O)CC2OC(=O)C[C@@H]21)(C(C)C)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.34
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
THRB P10828 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL455958 1.00 RAB9A (0.34) RAB9AKDM4ENPC1SMN1; SMN2THRB
SCHEMBL10989953 0.83 TOP2A (0.37) RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL8412572 0.83 TOP2A (0.37) RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL15193068 0.83 TOP2A (0.37) RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL13614213 0.81 RAB9A (0.38) RAB9AKDM4ENPC1SMN1; SMN2THRB
SCHEMBL16976870 0.80 RAB9A (0.38) RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL16976823 0.80 RAB9A (0.38) RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL12035124 0.78 RAB9A (0.38) RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL441609 0.76 RAB9A (0.37) RAB9AKDM4ENPC1SMN1; SMN2THRB
SCHEMBL13531627 0.76 RAB9A (0.34) RAB9AKDM4ENPC1SMN1; SMN2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010083597-A1 METHODS OF MAKING LUBIPROSTONE AND INTERMEDIATES THEREOF APOTEX PHARMACHEM INC. (CA) 2010-07-29 WO disclosed