SCHEMBL371216

SCHEMBL371216

CCCCCN1C(=O)CCC1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.70
FAAH O00519 3/20 0.70
PTGS1 P23219 3/20 0.54
PTGS2 P35354 3/20 0.54
MEN1 O00255 1/20 0.47
POLB P06746 1/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
CYP19A1 P11511 11/20 0.45
CHRM2 P08172 1/20 0.45
CHRM4 P08173 1/20 0.45
CHRM5 P08912 1/20 0.45
CHRM1 P11229 1/20 0.45
DRD2 P14416 1/20 0.45
CHRM3 P20309 1/20 0.45
DRD4 P21917 1/20 0.45
DRD3 P35462 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31452685 0.98 MGLL (0.68) MGLLFAAHPTGS1PTGS2MEN1
SCHEMBL7035034 0.98 MGLL (0.68) MGLLFAAHPTGS1PTGS2MEN1
SCHEMBL735230 0.98 MGLL (0.68) MGLLFAAHPTGS1PTGS2MEN1
SCHEMBL9307539 0.98 MGLL (0.68) MGLLFAAHPTGS1PTGS2MEN1
SCHEMBL40386 0.98 MGLL (0.68) MGLLFAAHPTGS1PTGS2MEN1
SCHEMBL7198335 0.98 MGLL (0.68) MGLLFAAHPTGS1PTGS2MEN1
SCHEMBL8863096 0.98 MGLL (0.68) MGLLFAAHPTGS1PTGS2MEN1
SCHEMBL5970073 0.98 MGLL (0.68) MGLLFAAHPTGS1PTGS2MEN1
SCHEMBL8862894 0.98 MGLL (0.68) MGLLFAAHPTGS1PTGS2MEN1
SCHEMBL734753 0.98 MGLL (0.68) MGLLFAAHPTGS1PTGS2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112028919-A B (3)/B (3,6) -o-carborane alkylation method of compound 南京大学 2020-12-04 CN claimed
CN-109077993-A A kind of lacrimal sustained-release hydrogel implant and preparation method thereof 北京诺康达医药科技股份有限公司 2018-12-25 CN claimed
CN-104399109-B A kind of gel hemostatic material composition and preparation method thereof 沈伟 2018-02-02 CN claimed
CN-105037523-A Interferon mutant and polyethylene glycol derivative thereof BEIJING TRI PRIME GENETIC ENG 2015-11-11 CN claimed
EP-0591861-B1 Reactivity control in microcrystalline coupler dispersions EASTMAN KODAK CO (US) 1999-07-28 EP claimed
US-5609848-A Radiohalogenated small molecules for protein labeling NEORX CORPORATION (US) 1997-03-11 US claimed
US-5200169-A Vinyl substituted radiohalogen conjugates for protein labeling NEORX CORPORATION (US) 1993-04-06 US claimed
EP-0203764-B1 RADIOHALOGENATED SMALL MOLECULES FOR PROTEIN LABELING NEORX CORPORATION (US) 1993-03-24 EP claimed
US-5045303-A Radiohalogenated small molecules for protein labeling NEORX CORPORATION (US) 1991-09-03 US claimed
US-4885153-A Radiohalogenated for proteins NEORX CORPORATION (US) 1989-12-05 US claimed
EP-0289187-A2 Vinyl substituted radiohalogen conjugates for protein labeling NEORX CORPORATION (US) 1988-11-02 EP claimed
EP-0203764-A2 Radiohalogenated small molecules for protein labeling NEORX CORPORATION (US) 1986-12-03 EP claimed
JP-9176084-A None JP disclosed
JP-8239674-A None JP disclosed
CN-115826360-B Photosensitive polyimide composition, method for producing pattern, cured product, and electronic component 江苏艾森半导体材料股份有限公司 2023-09-12 CN disclosed
US-20220301563-A1 Method of Contextual Speech Decoding from the Brain THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-09-22 US disclosed
EP-0048096-A1 Beta-lactam antibacterial agents BEECHAM GROUP PLC (GB) 1982-03-24 EP disclosed
US-4297438-A USING HYDROPHILIC AND HYDROPHOBIC DEVELOPERS COMPRISING N-SULFOALKYL-N-ALKYL-P-DIAMINOBENZENES AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed
US-4038082-A IMAGE-RECEIVING MATERIAL FOR COLOR DIFFUSION TRANSFER COMPRISING PVA AND POLYMETHYLOL COMPOUNDS FUJI PHOTO FILM CO., LTD. (JA) 1977-07-26 US disclosed
US-3933831-A Perfluorinated tertiary amines PCR, INC. (US) 1976-01-20 US disclosed