Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH2 | Q9NR71 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CETP | P11597 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.50 |
| ▸ | CCR6 | P51684 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712347 | 1.00 | ASAH2 (0.74) | ASAH2MAPTTP53CYP2D6MAPK1 | |
| SCHEMBL3712341 | 1.00 | ASAH2 (0.74) | ASAH2MAPTTP53CYP2D6MAPK1 | |
| SCHEMBL3712345 | 1.00 | ASAH2 (0.74) | ASAH2MAPTTP53CYP2D6MAPK1 | |
| SCHEMBL30654713 | 0.85 | ASAH2 (1.00) | ASAH2MAPTTP53CYP2D6MAPK1 | |
| SCHEMBL18506537 | 0.85 | ASAH2 (1.00) | ASAH2MAPTTP53CYP2D6MAPK1 | |
| SCHEMBL30145483 | 0.85 | ASAH2 (1.00) | ASAH2MAPTTP53CYP2D6MAPK1 | |
| SCHEMBL13849917 | 0.85 | ASAH2 (1.00) | ASAH2MAPTTP53CYP2D6MAPK1 | |
| SCHEMBL27013983 | 0.85 | ASAH2 (1.00) | ASAH2MAPTTP53CYP2D6MAPK1 | |
| SCHEMBL29967428 | 0.84 | ASAH2 (0.97) | ASAH2TP53CETPMEN1KMT2A | |
| SCHEMBL12227954 | 0.84 | ASAH2 (0.97) | ASAH2TP53CETPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010085547-A2 | METHODS OF PREPARING 1-DEOXY-SPHINGOID BASES AND DERIVATIVES THEREOF | EMORY UNIVERSITY (US) | 2010-07-29 | — | — | WO | disclosed |