SCHEMBL3712447

SCHEMBL3712447

CC1(C)NCC(C(=O)O)S1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.33
HTT P42858 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8313692 0.62 KMT2A (0.36) APLNRHTT
SCHEMBL10716500 0.60 APLNR (0.32) APLNRHTT
SCHEMBL468398 0.59 TSHR (0.35) CYP1A2CYP2D6CYP2C19
SCHEMBL25955125 0.58 APLNR (0.50) APLNRCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL10640937 0.57
SCHEMBL23115271 0.56 POLB (0.30)
SCHEMBL1487444 0.56 APLNR (0.33) APLNRHTTCYP1A2CYP2C19
SCHEMBL4321495 0.56 HTT (0.52) APLNRHTTCYP1A2CYP2D6CYP2C19
SCHEMBL8632263 0.56 APLNR (0.33) APLNRHTTCYP1A2CYP2C19
SCHEMBL14506000 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117202938-A Variant Fc domains and uses thereof 奇达拉治疗公司 2023-12-08 CN disclosed
CN-114980933-A Compositions and methods for treating viral infections 奇达拉治疗公司 2022-08-30 CN disclosed
CN-114728937-A Compositions and methods for treating respiratory syncytial virus 奇达拉治疗公司 2022-07-08 CN disclosed
CN-114599389-A Variant FC domains and uses thereof 奇达拉治疗公司 2022-06-07 CN disclosed
CN-114401731-A Compositions and methods for treating human immunodeficiency virus 奇达拉治疗公司 2022-04-26 CN disclosed
CN-114390929-A Compositions and methods for treating respiratory syncytial virus 奇达拉治疗公司 2022-04-22 CN disclosed
CN-114302741-A Compositions and methods for treating autoimmune disorders 密执安大学评议会 2022-04-08 CN disclosed
CN-113194983-A Compositions and methods for treating viral infections 奇达拉治疗公司 2021-07-30 CN disclosed
CN-104230900-A Antiviral compounds GILEAD SCIENCES INC 2014-12-24 CN disclosed
CN-104211689-A Antiviral compounds GILEAD SCIENCES INC 2014-12-17 CN disclosed
EP-2398492-A1 CYTOTOXIC CONJUGATES HAVING NEUROPEPTIDE Y RECEPTOR BINDING COMPOUND IPSEN PHARMA S.A.S. (FR) 2011-12-28 EP disclosed
WO-2010096175-A1 CYTOTOXIC CONJUGATES HAVING NEUROPEPTIDE Y RECEPTOR BINDING COMPOUND IPSEN PHARMA S.A.S. (FR) 2010-08-26 WO disclosed
EP-1881982-A1 IMIDAZOLONE PHENYLALANINE DERIVATIVES AS VLA-4 ANTAGONISTS Elan Pharmaceuticals Inc. (US) 2008-01-30 EP disclosed
CN-1913889-A Compositions comprising HIV protease inhibitor and cytochrome P450 enzyme activity inhibitor PFIZER (US) 2007-02-14 CN disclosed
WO-2006127584-A1 IMIDAZOLONE PHENYLALANINE DERIVATIVES AS VLA-4 ANTAGONISTS ELAN PHARMACEUTICALS, INC. (US) 2006-11-30 WO disclosed
CN-1550496-A Acetylenic alpha-amino acid-based sulfamide hydroxamic acid TACE inhibitors ���Ͽع����޹�˾ 2004-12-01 CN disclosed
CN-1345308-A Acetylenic alpha-amino acid based sulfonamide hydroxamic acid TACE inhibitors AMERICAN CYANAMID CO (US) 2002-04-17 CN disclosed
EP-0668875-A4 CLOT DIRECTED ANTICOAGULANT, PROCESS FOR MAKING SAME AND METHODS OF USE. AGEN LTD (AU) 1999-05-26 EP disclosed
EP-0668875-A1 CLOT DIRECTED ANTICOAGULANT, PROCESS FOR MAKING SAME AND METHODS OF USE AGEN LIMITED (AU) 1995-08-30 EP disclosed
WO-1994009034-A1 CLOT DIRECTED ANTICOAGULANT, PROCESS FOR MAKING SAME AND METHODS OF USE AGEN LIMITED (AU) 1994-04-28 WO disclosed