Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288521 | 0.87 | MEN1 (0.46) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL8066551 | 0.85 | MEN1 (0.44) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL23035421 | 0.83 | ALDH1A1 (0.42) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL29860351 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HIF1ATDP1CYP3A4MAPT | |
| SCHEMBL1340438 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HIF1ATDP1CYP3A4MAPT | |
| SCHEMBL18956810 | 0.80 | MEN1 (0.41) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL28659258 | 0.80 | TSHR (0.52) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL30391542 | 0.80 | MEN1 (0.41) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL23152122 | 0.80 | ALDH1A1 (0.44) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL239430 | 0.80 | MEN1 (0.41) | MEN1KMT2AUSP2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085852-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-8-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012085857-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-3-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | disclosed |
| WO-2010094415-A1 | FLUORINE CONTAINING REACTIVE DYES | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2010-08-26 | — | — | WO | disclosed |
| CN-1902057-A | Optical recording medium and dye | MITSUBISHI CHEM CORP (JP) | 2007-01-24 | — | — | CN | disclosed |
| US-20060223003-A1 | Optical recording medium and dye | MITSUBISHI CHEMICAL CORPORATION (JP) | 2006-10-05 | — | — | US | disclosed |
| EP-1698478-A1 | OPTICAL RECORDING MEDIUM AND DYE | Mitsubishi Chemical Corporation (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2004046118-A2 | 2-4-(DI-PHENYL-AMINO)-PYRIMIDINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223003-A1 | Optical recording medium and dye | CHRM1, CACNA1S, OXER1 | MEN1 3917/4885KMT2A 2763/4885USP2 4697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.