Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 3/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 3/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305333 | 0.89 | KDM4E (0.59) | KDM4ETDP1DHODHNAPRTSMO | |
| SCHEMBL3712467 | 0.82 | KDM4E (0.67) | KDM4ETDP1KMT2ADHODHNAPRT | |
| SCHEMBL2802417 | 0.78 | CYP19A1 (0.52) | KDM4ETDP1MEN1KMT2ANPC1 | |
| SCHEMBL8308388 | 0.78 | KMO (0.62) | KDM4ETDP1NPC1RAB9AKMO | |
| SCHEMBL8307098 | 0.78 | KMO (0.62) | KDM4ETDP1MEN1KMT2ANPC1 | |
| SCHEMBL25780881 | 0.77 | KDM4E (0.80) | KDM4ETDP1NPC1RAB9ADHODH | |
| SCHEMBL4902003 | 0.77 | MEN1 (0.69) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2797699 | 0.75 | CYP19A1 (0.55) | KDM4ETDP1MEN1KMT2ANPC1 | |
| SCHEMBL4903205 | 0.74 | KMO (0.57) | MEN1KMT2ANPC1RAB9AATM | |
| SCHEMBL8307172 | 0.74 | KDM4E (0.53) | KDM4ETDP1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739341-B1 | HERBICIDAL ARYL AND HETEROARYL PYRIMIDINES | NOVARTIS AG (CH) | 1999-06-02 | — | — | EP | disclosed |
| EP-0739341-A1 | HERBICIDAL ARYL AND HETEROARYL PYRIMIDINES | Novartis AG (CH) | 1996-10-30 | — | — | EP | disclosed |
| WO-1995019358-A1 | HERBICIDAL ARYL AND HETEROARYL PYRIMIDINES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | disclosed |