SCHEMBL3712484

SCHEMBL3712484

OCC(c1cccc(Br)c1)c1cccs1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSA P10619 1/20 0.39
IDO1 P14902 1/20 0.37
TDO2 P48775 1/20 0.37
TSHR P16473 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
SLC6A3 Q01959 3/20 0.34
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
SLC18A3 Q16572 1/20 0.33
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28096029 0.81 CTSA (0.45) CTSANPC1MGAMGAASI
SCHEMBL3908791 0.81 TSHR (0.42) TSHRNPC1RAB9ASLC6A3MGAM
SCHEMBL7605334 0.81 IDO1 (0.47) CTSAIDO1TDO2SLC6A3MGAM
SCHEMBL17295946 0.78 IDO1 (0.49) CTSAIDO1TDO2KMT2AMGAM
SCHEMBL28202930 0.77 DAO (0.43) TSHRNPC1RAB9AKMT2AMGAM
Methyl Alcohol SCHEMBL28201444 0.76 CTSA (0.36) CTSAIDO1TDO2TSHRNPC1
SCHEMBL17398472 0.73 SLC6A4 (0.38) CTSAIDO1TDO2SLC6A3MGAM
SCHEMBL5858340 0.70 IDO1 (0.43) CTSAIDO1TDO2SLC6A3SLC18A3
SCHEMBL17398372 0.70 CTSA (0.38) CTSAIDO1TDO2SLC6A3MGAM
SCHEMBL3398813 0.69 MAOB (0.48) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2396295-A1 PHENOXY ACETIC ACID DERIVATIVES Merck Serono S.A. (CH) 2011-12-21 EP disclosed
WO-2010092043-A1 PHENOXY ACETIC ACID DERIVATIVES MERCK SERONO S.A. (CH) 2010-08-19 WO disclosed