Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096025 | 0.85 | SLC6A3 (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27482821 | 0.84 | POLB (0.45) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL3712484 | 0.81 | CTSA (0.39) | CTSAMGAMGAASIMGAM2 | |
| SCHEMBL11254513 | 0.81 | CTSA (0.49) | CTSAMGAMGAASIMGAM2 | |
| SCHEMBL28096032 | 0.75 | L3MBTL1 (0.47) | GAAALDH1A1NPC1FFAR1POLB | |
| Methyl Alcohol SCHEMBL28201444 | 0.74 | CTSA (0.36) | CTSAALDH1A1NPC1POLBSMN1; SMN2 | |
| SCHEMBL15427663 | 0.73 | ALDH1A1 (0.44) | CTSAMGAMGAASIMGAM2 | |
| SCHEMBL27633523 | 0.73 | L3MBTL1 (0.49) | CTSA | |
| SCHEMBL27633524 | 0.73 | L3MBTL1 (0.49) | CTSA | |
| SCHEMBL8194313 | 0.73 | ALDH1A1 (0.44) | CTSAMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105924425-B | A kind of method for preparing dihydro sulphur chroman derivative | 浙江师范大学 | 2018-06-05 | — | — | CN | disclosed |
| CN-105924425-A | Preparation method of dihydrothiochroman derivative | 浙江师范大学 | 2016-09-07 | — | — | CN | disclosed |