Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3152790 | 1.00 | RXFP1 (0.44) | RXFP1SENP1SMN1; SMN2GAANPC1 | |
| SCHEMBL2122227 | 1.00 | RXFP1 (0.44) | RXFP1SENP1SMN1; SMN2GAANPC1 | |
| SCHEMBL3153345 | 0.95 | RXFP1 (0.45) | RXFP1SENP1SMN1; SMN2GAANPC1 | |
| SCHEMBL3153335 | 0.95 | RXFP1 (0.45) | RXFP1SENP1SMN1; SMN2GAANPC1 | |
| SCHEMBL2568541 | 0.92 | SENP1 (0.39) | SENP1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL2568543 | 0.92 | SENP1 (0.39) | SENP1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL479383 | 0.91 | RXFP1 (0.42) | RXFP1SENP1SMN1; SMN2GAANPC1 | |
| SCHEMBL2566845 | 0.91 | RXFP1 (0.42) | RXFP1SENP1SMN1; SMN2GAANPC1 | |
| SCHEMBL479382 | 0.91 | RXFP1 (0.42) | RXFP1SENP1SMN1; SMN2GAANPC1 | |
| SCHEMBL2569460 | 0.91 | RXFP1 (0.44) | RXFP1SENP1SMN1; SMN2GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |