SENP1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL485085	0.58	19/20
SCHEMBL485651	0.57	19/20
SCHEMBL485276	0.46	19/20
SCHEMBL485260	0.56	18/20
SCHEMBL485298	0.56	18/20
SCHEMBL484955	0.47	18/20
SCHEMBL485732	0.46	18/20
SCHEMBL485458	0.59	17/20
SCHEMBL485661	0.47	17/20
SCHEMBL1000592	0.50	16/20
SCHEMBL1230808	0.50	14/20
SCHEMBL1023993	0.58	10/20
SCHEMBL1382397	0.47	10/20
SCHEMBL1000593	0.49	7/20
SCHEMBL110923	0.54	6/20
SCHEMBL110924	0.54	6/20
SCHEMBL1436156	0.54	6/20
SCHEMBL1436155	0.53	6/20
SCHEMBL414245	0.52	6/20
SCHEMBL347478	0.49	6/20

Clinical trials — most relevant to SENP1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Signal TrAnsduction Pathway Activity Analysis in OVarian cancER	PHASE2/PHASE3	RECRUITING
Phase II Prospective Cohort Study of Intravesical Recombinant Human Type 5 Adenovirus Injection for Treatment of High-Risk Non-Muscle Invasive Bladder Cancer: Evaluating Efficacy and Safety	PHASE2	NOT_YET_RECRUITING
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers	PHASE2	NOT_YET_RECRUITING
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety	PHASE2	COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck	PHASE1	COMPLETED
Extended Infusion Carfilzomib on a Weekly Schedule in Patients With Advanced Solid Tumors	PHASE1	COMPLETED
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis	nan	UNKNOWN
Evaluation of Prognostic Factors: From Breast Cancer to Bone Metastases	nan	UNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD)	nan	COMPLETED
Fatty Acid Binding Proteins and Markers of Cellular Senescence in Cancer Survivors	nan	NOT_YET_RECRUITING
Apoptosis Markers in Aggressive Periodontitis	nan	COMPLETED
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma	nan	COMPLETED
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure	nan	COMPLETED
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas	nan	RECRUITING
Autophagy Bladder Cancer	nan	UNKNOWN
Circulating Markers for Ischemic Heart Disease	nan	RECRUITING
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS	nan	COMPLETED
The Mechanisms and Significances of Synergistic Effects of Mycophenolic Acid and LPS on IL-1β Secretion by Mononuclear	nan	UNKNOWN
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study	nan	COMPLETED
Expression and Clinical Significance of IGHD in Pancreatic Cancer	nan	UNKNOWN
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS	nan	RECRUITING
Exosome-based Liquid Biopsies for Upper Gastrointestinal Cancers Diagnosis	nan	UNKNOWN
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Genetic Analysis to Predict the Development of Paget's Disease	nan	ACTIVE_NOT_RECRUITING
Genetic Basis of Mitral Valve Prolapse	nan	UNKNOWN
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men	nan	RECRUITING
Evaluation of Proteasome as a Marker of Hepatocellular Carcinoma in Cirrhotic Patients Following Curative Treatment	nan	UNKNOWN
Biological Markers in Parkinson's Disease	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a SENP1 binder may also engage these)

Protein	Name	Similarity
Q5RBB1	—	1.000	Q5RBB1 →
P59110	—	0.998	P59110 →
SENP2	Sentrin-specific protease 2	0.993	landscape →
Q5R7K7	—	0.992	Q5R7K7 →
P46200	—	0.991	P46200 →
P10244	—	0.991	P10244 →
A6QP06	—	0.990	A6QP06 →
Q2PFD7	—	0.989	Q2PFD7 →
Q9EQE1	—	0.989	Q9EQE1 →
MAP3K13	Mitogen-activated protein kinase kinase kinase 13	0.989	landscape →
Q91ZX6	—	0.989	Q91ZX6 →
Q6EEF3	—	0.989	Q6EEF3 →
B2GUY1	—	0.989	B2GUY1 →
CDKL5	Cyclin-dependent kinase-like 5	0.989	landscape →
Q76I79	—	0.988	Q76I79 →
Q8NEM8	—	0.988	Q8NEM8 →
Q3YC04	—	0.988	Q3YC04 →
Q811D2	—	0.988	Q811D2 →
Q5TKR9	—	0.988	Q5TKR9 →
Q9Z1J2	—	0.988	Q9Z1J2 →
Q92539	—	0.988	Q92539 →
BLM	RecQ-like DNA helicase BLM	0.988	landscape →
Q9NYI0	—	0.988	Q9NYI0 →
O43310	—	0.988	O43310 →
A0A1L8HFX9	—	0.987	A0A1L8HFX9 →
Q9SB51	—	0.987	Q9SB51 →
Q6NRK3	—	0.987	Q6NRK3 →
Q949U2	—	0.987	Q949U2 →
KMT5B	Histone-lysine N-methyltransferase KMT5B	0.987	landscape →
Q9NQW6	—	0.987	Q9NQW6 →