SCHEMBL3712698

SCHEMBL3712698

CCCc1nc2c(C)cc(C=O)cc2[nH]1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 2/20 0.38
ACACB O00763 1/20 0.36
ACACA Q13085 1/20 0.36
PRKCZ Q05513 1/20 0.34
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.32
MAPT P10636 1/20 0.32
CACNA1H O95180 1/20 0.32
ALDH1A1 P00352 1/20 0.31
KDM4C Q9H3R0 1/20 0.31
GLA P06280 1/20 0.31
PDE10A Q9Y233 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19342748 0.80 KDM4E (0.44) KMT2AKDM4EACACBACACAPRKCZ
SCHEMBL27809455 0.79 KMT2A (0.36) KMT2AKDM4EACACBACACAPRKCZ
SCHEMBL28080901 0.79 ACACB (0.36) KMT2AKDM4EACACBACACAPRKCZ
SCHEMBL1918148 0.77 EGLN1 (0.40) KMT2AKDM4EACACBACACAPRKCZ
SCHEMBL3712699 0.77 KMT2A (0.38) KMT2AKDM4EPOLBMAPK1MAPT
SCHEMBL158112 0.75 ACACB (0.45) KMT2AKDM4EACACBACACAPRKCZ
SCHEMBL3640946 0.75 ACACB (0.36) KMT2AKDM4EACACBACACAPRKCZ
SCHEMBL28048356 0.74 ACACB (0.44) KMT2AKDM4EACACBACACAPRKCZ
SCHEMBL8848140 0.74 ACACB (0.44) KMT2AKDM4EACACBACACAPRKCZ
SCHEMBL9754820 0.73 KMT2A (0.37) KMT2AKDM4EACACBACACAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113045501-B Preparation method of telmisartan intermediate 石家庄学院 2022-09-30 CN claimed
CN-113045501-A Preparation method of telmisartan intermediate 石家庄学院 2021-06-29 CN claimed
CN-113045501-B Preparation method of telmisartan intermediate 石家庄学院 2022-09-30 CN disclosed
CN-113045501-B Preparation method of telmisartan intermediate 石家庄学院 2022-09-30 CN disclosed
CN-113045501-A Preparation method of telmisartan intermediate 石家庄学院 2021-06-29 CN disclosed
CN-113045501-A Preparation method of telmisartan intermediate 石家庄学院 2021-06-29 CN disclosed
WO-2010081670-A2 PROCESS FOR THE PREPARATION OF BENZIMIDAZOLES LONZA LTD (CH) 2010-07-22 WO disclosed
WO-2009123483-A1 PROCESS FOR PREPARATION OF TELMISARTAN ZAKLADY FARMACEUTYCZNE POLPHARMA SA (PL) 2009-10-08 WO disclosed
WO-2009123483-A1 PROCESS FOR PREPARATION OF TELMISARTAN ZAKLADY FARMACEUTYCZNE POLPHARMA SA (PL) 2009-10-08 WO disclosed