Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19342748 | 0.83 | KDM4E (0.44) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL1918148 | 0.77 | EGLN1 (0.40) | KMT2AALDH1A1POLBKDM4EACACB | |
| SCHEMBL9754821 | 0.77 | ADORA1 (0.36) | KMT2AMEN1ALDH1A1POLBMAPK1 | |
| SCHEMBL14855819 | 0.75 | KMT2A (0.35) | KMT2AALDH1A1POLBKDM4EACACB | |
| SCHEMBL3640946 | 0.75 | ACACB (0.36) | KMT2AALDH1A1POLBKDM4EACACB | |
| SCHEMBL3712698 | 0.73 | KMT2A (0.38) | KMT2AALDH1A1POLBMAPK1KDM4E | |
| SCHEMBL17801869 | 0.73 | KDM4E (0.38) | KMT2AALDH1A1POLBKDM4EACACB | |
| SCHEMBL4553606 | 0.73 | ACACB (0.36) | KMT2AALDH1A1POLBKDM4EACACB | |
| Hydrochloric Acid SCHEMBL4437775 | 0.73 | ACACB (0.44) | KMT2AALDH1A1MAPK1KDM4EACACB | |
| SCHEMBL27809455 | 0.73 | KMT2A (0.36) | KMT2APOLBMAPK1KDM4EACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013063-A1 | NEW BENZIMIDAZOLE DERIVATIVES, METHOD FOR PREPARING THEM AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-09-05 | — | — | WO | disclosed |