Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPS1 | P31327 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GHSR | Q92847 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26835742 | 0.86 | CPS1 (0.53) | CPS1HTTMEN1KMT2ATSHR | |
| SCHEMBL26814699 | 0.86 | CPS1 (0.53) | CPS1HTTMEN1KMT2ATSHR | |
| SCHEMBL3712727 | 0.81 | HTT (0.62) | HTTTSHRGHSRLMNAALOX15 | |
| SCHEMBL1498918 | 0.79 | CPS1 (0.57) | CPS1HTTKMT2AGHSRLMNA | |
| SCHEMBL22720328 | 0.78 | CPS1 (0.53) | CPS1HTTTSHRGHSRLMNA | |
| SCHEMBL22720326 | 0.78 | CPS1 (0.53) | CPS1HTTTSHRGHSRLMNA | |
| SCHEMBL3711592 | 0.78 | GHSR (0.58) | CPS1HTTTSHRGHSRLMNA | |
| SCHEMBL28878111 | 0.78 | GHSR (0.58) | CPS1HTTTSHRGHSRLMNA | |
| SCHEMBL28878114 | 0.78 | GHSR (0.58) | CPS1HTTTSHRGHSRLMNA | |
| SCHEMBL27748956 | 0.78 | HTT (0.73) | HTTMEN1KMT2ATSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102663-A1 | PIPERAZINE DERIVATIVES FOR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |