SCHEMBL371328

SCHEMBL371328

C=CC([NH])O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30980 0.70
SCHEMBL6683657 0.70
SCHEMBL6693815 0.67
SCHEMBL15496478 0.67
SCHEMBL347195 0.67
Ammonia Solution, Strong SCHEMBL4908314 0.67
SCHEMBL45611 0.67
SCHEMBL3416266 0.67
SCHEMBL2893448 0.67
SCHEMBL887097 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 969 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018163-A1 NEW THIAZOLOPYRIMIDINONE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2024-01-18 US claimed
CN-116903613-A 2-oxo quinazoline five-membered heterocyclic derivative, preparation method and application thereof 深圳微芯生物科技股份有限公司 2023-10-20 CN claimed
WO-2023175932-A1 THERAPEUTIC AGENT FOR HIGH-RISK MYELOFIBROSIS 日本新薬株式会社 2023-09-21 WO claimed
WO-2023176972-A1 THERAPEUTIC AGENT FOR HIGH-RISK MYELOFIBROSIS 日本新薬株式会社 2023-09-21 WO claimed
CN-114727931-A Composition for caring for/making up keratin fibres 莱雅公司 2022-07-08 CN claimed
EP-3902787-A1 QUINAZOLINE DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS Riboscience LLC (US) 2021-11-03 EP claimed
EP-3390608-B1 LIQUID DETERGENTS OR CLEANING AGENTS CONTAINING ACYL HYDRAZONE HENKEL AG & CO KGAA (DE) 2021-07-07 EP claimed
WO-2021102886-A1 COMPOSITION FOR CARING FOR/MAKING UP KERATAIN FIBERS L'OREAL (FR) 2021-06-03 WO claimed
WO-2020140001-A1 QUINAZOLINE DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS RIBOSCIENCE LLC (US) 2020-07-02 WO claimed
CN-111032007-A Method for dyeing keratin fibres using at least one direct dye and at least one fluorescent dye chosen from disulfides, thiols and protected thiols 莱雅公司 2020-04-17 CN claimed
CN-86105641-A The method for preparing antianaphylaxis and antibronchospasm of N-dibenzyl-diazacyclo alkyl-alkyl-anilide 1987-04-01 CN claimed
US-4603133-A Amides and esters of 2-[N-(morpholinoalkyl)aminosulfonyl]-6-nitrobenzoic acids and compositions useful as adjuncts to radiation therapy MERCK & CO., INC. (US) 1986-07-29 US claimed
EP-0017937-B1 BONDING COMPOSITIONS TO THE HARD TISSUE OF HUMAN BODY KANEBO, LTD. (JP) 1985-04-24 EP claimed
US-4361516-A N-Monosubstituted indoanilines SOCIETE ANONYME DITE: L'OREAL (FR) 1982-11-30 US claimed
US-4321207-A Process for preparing triarylmethane dyes AMERICAN CYANAMID COMPANY (US) 1982-03-23 US claimed
US-4222958-A HAIR DYES L'OREAL (FR) 1980-09-16 US claimed
US-4144336-A 2-Benzopyranone derivatives, process for their production, their use as medicaments, more especially as coronary dilators TROPONWERKE DINKLAGE & CO. (DE) 1979-03-13 US claimed
US-4054147-A 4,4-Disubstituted diphenylamines in dye compositions for keratinic fibers L'OREAL (FR) 1977-10-18 US claimed
US-4008999-A N,N-dialkylamino diphenylamines for dyeing keratinic fibers SOCIETE ANONYME DITE: L'OREAL (FR) 1977-02-22 US claimed
US-4007747-A HAIR DYES SOCIETE ANONYME DITE: L'OREAL (FR) 1977-02-15 US claimed