Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 14/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709625 | 0.87 | SLC9A1 (0.55) | SLC9A1ALDH1A1HPGDS1PR4S1PR5 | |
| SCHEMBL4943681 | 0.81 | SLC9A1 (0.67) | SLC9A1ALDH1A1HPGDS1PR4S1PR5 | |
| SCHEMBL3711899 | 0.79 | SLC9A1 (0.59) | SLC9A1ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL4943685 | 0.79 | SLC9A1 (1.00) | SLC9A1ALDH1A1HPGD | |
| SCHEMBL3722093 | 0.78 | SLC9A1 (0.54) | SLC9A1ALDH1A1HPGDS1PR4S1PR5 | |
| SCHEMBL3786003 | 0.76 | SLC9A1 (0.57) | SLC9A1ALDH1A1HPGD | |
| SCHEMBL3711321 | 0.76 | SLC9A1 (0.55) | SLC9A1ALDH1A1S1PR4S1PR5S1PR2 | |
| SCHEMBL3713569 | 0.73 | SLC9A1 (0.61) | SLC9A1ALDH1A1HPGDS1PR4S1PR5 | |
| SCHEMBL3712694 | 0.73 | SLC9A1 (0.61) | SLC9A1ALDH1A1S1PR4MAPTS1PR2 | |
| SCHEMBL3719608 | 0.73 | SLC9A1 (0.59) | SLC9A1ALDH1A1HPGDS1PR4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | claimed |
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | disclosed |