Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL406309 | 0.83 | CYP1A2 (0.42) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL10192898 | 0.74 | CYP1A2 (0.41) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL3711750 | 0.72 | HTR2A (0.40) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL401462 | 0.72 | CYP1A2 (0.41) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL407385 | 0.72 | CYP1A2 (0.39) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL21471161 | 0.71 | HTT (0.58) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL10195149 | 0.71 | CYP1A2 (0.40) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL10195186 | 0.69 | ALDH1A1 (0.40) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL10196017 | 0.69 | CYP1A2 (0.39) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL15935636 | 0.69 | ALDH1A1 (0.39) | CYP1A2CYP2C19CYP2C9ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393796-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089211-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-12 | — | — | WO | disclosed |