Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 2/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710012 | 0.88 | GPR119 (0.41) | GPR119KITPIK3CDHRH3IKBKB | |
| SCHEMBL3717083 | 0.86 | PDE4B (0.43) | GPR119 | |
| SCHEMBL3713593 | 0.86 | PDE4B (0.43) | GPR119 | |
| SCHEMBL3710674 | 0.83 | GPR119 (0.43) | GPR119PIK3CDHRH3IKBKBTLR9 | |
| SCHEMBL3915607 | 0.83 | KIT (0.38) | GPR119KIT | |
| SCHEMBL3908051 | 0.83 | KIT (0.38) | GPR119KIT | |
| SCHEMBL3715196 | 0.81 | GPR119 (0.38) | GPR119PIK3CDIKBKBTLR9TLR8 | |
| SCHEMBL3651433 | 0.79 | HRH1 (0.44) | GPR119 | |
| SCHEMBL3913434 | 0.74 | KIT (0.37) | KITHRH3 | |
| SCHEMBL3710011 | 0.73 | PDE4B (0.44) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |