Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119560 | 1.00 | RXFP1 (0.46) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL479663 | 0.92 | RAB9A (0.39) | RXFP1GAANPC1RAB9AMAPT | |
| SCHEMBL480541 | 0.91 | RXFP1 (0.47) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL2573629 | 0.91 | RXFP1 (0.49) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL480592 | 0.88 | RXFP1 (0.47) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL479307 | 0.87 | RXFP1 (0.47) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL2119035 | 0.87 | RXFP1 (0.47) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL2120156 | 0.87 | RXFP1 (0.47) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL479845 | 0.87 | RXFP1 (0.47) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL480669 | 0.87 | RXFP1 (0.47) | RXFP1SMN1; SMN2GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |