Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.70 |
| ▸ | LCK | P06239 | 1/20 | 0.70 |
| ▸ | FYN | P06241 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10704268 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL16431962 | 1.00 | FFAR3 (0.70) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL28225615 | 0.95 | FFAR3 (0.78) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL28407244 | 0.95 | FFAR3 (0.78) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL26969214 | 0.95 | FFAR3 (0.78) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL9571190 | 0.95 | — | — | |
| Acetic Acid SCHEMBL9806973 | 0.95 | — | — | |
| Acetic Acid SCHEMBL16735521 | 0.95 | — | — | |
| Acetic Acid SCHEMBL29023793 | 0.95 | FFAR3 (0.78) | FFAR3LCKFYNCA1CA2 | |
| Acetic Acid SCHEMBL9516924 | 0.95 | FFAR3 (0.78) | FFAR3LCKFYNCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097675-A1 | AN IMPROVED PREPARATION PROCESS FOR CEFPODOXIME PROXETIL | DHANUKA LABORATORIES LTD. (IN) | 2010-09-02 | — | — | WO | claimed |
| CN-110114350-A | Substituted guanidine compounds | 宇部兴产株式会社 | 2019-08-09 | — | — | CN | disclosed |
| CN-110024191-A | Binder composition for nonaqueous electrolyte battery electrode, hydrogel using same as raw material, slurry composition for nonaqueous electrolyte battery electrode using same, nonaqueous electrolyte battery negative electrode, and nonaqueous electrolyte battery | 株式会社可乐丽 | 2019-07-16 | — | — | CN | disclosed |
| CN-107925084-A | Binder composition for nonaqueous electrolyte battery, slurry composition for nonaqueous electrolyte battery using same, negative electrode for nonaqueous electrolyte battery, and nonaqueous electrolyte battery | 株式会社可乐丽 | 2018-04-17 | — | — | CN | disclosed |
| CN-107925085-A | Binder composition for nonaqueous electrolyte battery, slurry composition for nonaqueous electrolyte battery using same, negative electrode for nonaqueous electrolyte battery, and nonaqueous electrolyte battery | 株式会社可乐丽 | 2018-04-17 | — | — | CN | disclosed |
| CN-107922379-A | Substituted guanidine derivatives | 宇部兴产株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-105764888-B | A kind of new 3 azabicyclos [3.1.0] hexame derivatives and its medical usage | 株式会社三和化学研究所 | 2018-04-06 | — | — | CN | disclosed |
| CN-107851779-A | Nonaqueous electrolyte battery slurry composition for electrode and use its nonaqueous electrolyte battery positive pole and nonaqueous electrolyte battery | 株式会社可乐丽 | 2018-03-27 | — | — | CN | disclosed |
| CN-107428687-A | Novel crystal of salt of 3-azabicyclo [3.1.0] hexane derivative and medical application thereof | 株式会社三和化学研究所 | 2017-12-01 | — | — | CN | disclosed |
| CN-107112541-A | Binder composition for lithium ion secondary battery negative electrode, slurry composition for lithium ion secondary battery negative electrode using same, lithium ion secondary battery negative electrode, and lithium ion secondary battery | 株式会社可乐丽 | 2017-08-29 | — | — | CN | disclosed |
| CN-105764888-A | Novel 3-azabicyclo[3.1.0]hexane derivative and use thereof for medical purposes | 株式会社三和化学研究所 | 2016-07-13 | — | — | CN | disclosed |