SCHEMBL3714514

SCHEMBL3714514

CC1=CCCC(C)(C)C1/C=C(\C)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
CYP3A4 P08684 1/20 0.54
ALOX15 P16050 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
KDM4E B2RXH2 1/20 0.43
GAA P10253 1/20 0.43
GABRA1 P14867 1/20 0.32
TSHR P16473 1/20 0.32
GABRG2 P18507 1/20 0.32
RXRA P19793 1/20 0.32
GABRB3 P28472 1/20 0.32
RXRB P28702 1/20 0.32
GABRB2 P47870 1/20 0.32
RXRG P48443 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891912 0.89 ALDH1A1 (0.55) ALDH1A1CYP3A4ALOX15TDP1KDM4E
SCHEMBL160941 0.89 ALDH1A1 (0.55) ALDH1A1CYP3A4ALOX15TDP1KDM4E
SCHEMBL2857543 0.84 ALDH1A1 (0.60) ALDH1A1CYP3A4ALOX15TDP1KDM4E
SCHEMBL2857545 0.84 ALDH1A1 (0.60) ALDH1A1CYP3A4ALOX15TDP1KDM4E
SCHEMBL12494396 0.82 ALDH1A1 (0.56) ALDH1A1CYP3A4ALOX15TDP1KDM4E
SCHEMBL22245027 0.82 ALDH1A1 (0.52) ALDH1A1CYP3A4ALOX15TDP1KDM4E
SCHEMBL5127833 0.82 ALDH1A1 (0.46) ALDH1A1CYP3A4ALOX15TDP1KDM4E
SCHEMBL3721176 0.82 ALDH1A1 (0.46) ALDH1A1CYP3A4ALOX15TDP1KDM4E
SCHEMBL244550 0.79 ALDH1A1 (0.54) ALDH1A1CYP3A4ALOX15TDP1KDM4E
SCHEMBL17923373 0.78 ALDH1A1 (0.60) ALDH1A1CYP3A4ALOX15TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2417095-B1 CARBOXYLIC DERIVATIVES AS VIOLET AND/OR WOODY ODORANT FIRMENICH & CIE (CH) 2015-01-14 EP disclosed
US-8183194-B2 Carboxylic derivatives as violet and/or woody odorant FIRMENICH SA (CH) 2012-05-22 US disclosed
WO-2010116286-A1 CARBOXYLIC DERIVATIVES AS VIOLET AND/OR WOODY ODORANT FIRMENICH SA (CH) 2010-10-14 WO disclosed