Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371459 | 1.00 | PDE4D (0.51) | PDE4DBCHEACHEPDPK1MTOR | |
| SCHEMBL14180093 | 0.89 | TACR1 (0.45) | PDE4DBCHEACHEPDPK1MTOR | |
| SCHEMBL14180132 | 0.89 | PDE4D (0.50) | PDE4DBCHEACHEPDPK1MTOR | |
| SCHEMBL11040038 | 0.88 | BCHE (0.55) | PDE4DBCHEACHEPDPK1MTOR | |
| SCHEMBL23049083 | 0.85 | BCHE (0.48) | PDE4DBCHEACHEPDPK1MTOR | |
| SCHEMBL14180108 | 0.83 | BCHE (0.49) | PDE4DBCHEACHEPDPK1MTOR | |
| SCHEMBL371469 | 0.83 | BCHE (0.49) | PDE4DBCHEACHEPDPK1MTOR | |
| SCHEMBL30171080 | 0.83 | BCHE (0.49) | PDE4DBCHEACHEPDPK1MTOR | |
| SCHEMBL12152898 | 0.83 | BCHE (0.49) | PDE4DBCHEACHEPDPK1MTOR | |
| SCHEMBL13562761 | 0.83 | BCHE (0.49) | PDE4DBCHEACHEPDPK1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120093875-A1 | AMINOCYCLITOL COMPOUNDS, PROCESS FOR OBTAINING THEM AND USES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2012-04-19 | — | — | US | disclosed |
| EP-2409966-A1 | AMINOCYCLITOL COMPOUNDS, PROCEDURE FOR THE OBTAINMENT AND USES | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2012-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120093875-A1 | AMINOCYCLITOL COMPOUNDS, PROCESS FOR OBTAINING THEM AND USES | AADAT, NFATC1, PBK | PDE4D 2261/4885BCHE 3251/4885ACHE 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.