Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 8/20 | 0.46 |
| ▸ | PYGL | P06737 | 3/20 | 0.46 |
| ▸ | PYGM | P11217 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19226203 | 0.78 | PYGB (0.44) | PYGBPYGLPYGM | |
| SCHEMBL14502563 | 0.78 | PYGB (0.44) | PYGBPYGLPYGM | |
| SCHEMBL18890762 | 0.78 | PYGB (0.44) | PYGBPYGLPYGM | |
| SCHEMBL14502562 | 0.78 | PYGB (0.44) | PYGBPYGLPYGM | |
| SCHEMBL13594841 | 0.78 | PYGB (0.44) | PYGBPYGLPYGM | |
| SCHEMBL24924778 | 0.78 | PYGB (0.44) | PYGBPYGLPYGM | |
| SCHEMBL14502578 | 0.78 | PYGB (0.44) | PYGBPYGLPYGM | |
| SCHEMBL3172797 | 0.77 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL12581436 | 0.77 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL454317 | 0.77 | PYGB (0.43) | PYGBPYGLPYGMLMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102673-A1 | HELLEBRIN AND HELLEBRIGENIN DERIVATIVES | UNIBIOSCREEN S.A. (BE) | 2010-09-16 | — | — | WO | disclosed |