Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188964 | 0.84 | RECQL (0.57) | RECQLTET2GAATSHRHSD17B10 | |
| SCHEMBL3709329 | 0.82 | GAA (0.53) | RECQLGAAMGAMSIMGAM2 | |
| SCHEMBL13188955 | 0.81 | RECQL (0.63) | RECQLTET2GAATSHRALDH1A1 | |
| SCHEMBL13246470 | 0.78 | RECQL (0.64) | RECQLTET2GAATSHRHSD17B10 | |
| SCHEMBL204758 | 0.77 | GAA (0.50) | RECQLTET2GAAMGAMSI | |
| SCHEMBL23643337 | 0.76 | RECQL (0.35) | RECQLGAACA12CA2 | |
| SCHEMBL20802464 | 0.76 | MEN1 (0.46) | RECQLGAAALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL13309270 | 0.76 | EPHX1 (0.39) | RECQLTET2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL13602806 | 0.75 | GAA (0.63) | RECQLTET2GAAMGAMSI | |
| SCHEMBL27807390 | 0.75 | GAA (0.48) | RECQLTET2GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100144-A1 | FUSED BICYCLIC COMPOUNDS AS INHIBITORS FOR PI3 KINASE | MERCK SERONO S.A. (CH) | 2010-09-10 | — | — | WO | disclosed |