Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778641 | 0.83 | HTT (0.36) | TSHRITGA4 | |
| SCHEMBL29056026 | 0.81 | DAO (0.30) | DAOTSHRNAPRT | |
| SCHEMBL10726304 | 0.76 | MEN1 (0.31) | — | |
| SCHEMBL28201086 | 0.73 | — | — | |
| SCHEMBL28488959 | 0.72 | MEN1 (0.30) | — | |
| SCHEMBL27964340 | 0.72 | — | — | |
| SCHEMBL27669692 | 0.70 | TSHR (0.33) | DAOTSHRNAPRT | |
| SCHEMBL28682085 | 0.69 | GAA (0.34) | — | |
| SCHEMBL7068822 | 0.68 | DAO (0.34) | DAOTSHRNAPRT | |
| SCHEMBL30237619 | 0.68 | PIM1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897315-B2 | Method for producing 8-methoxy-quinolinecarboxylic acids | BAYER HEALTHCARE AKTIENGESELLSCHAFT (DE) | 2005-05-24 | — | — | US | claimed |
| EP-1034173-B1 | METHOD FOR PRODUCING 8-METHOXY-QUINOLINE CARBOXYLIC ACIDS | BAYER HEALTHCARE AG (DE) | 2005-04-27 | — | — | EP | claimed |
| US-20030208069-A1 | Method for producing 8-methoxy-quinoline carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-06 | — | — | US | claimed |
| EP-0657448-B1 | One pot process for the preparation of 3-quinolonecarboxylic acid derivatives | BAYER AG (DE) | 1998-03-04 | — | — | EP | claimed |
| US-5639886-A | One-pot process for the preparation of 3-quinolonecarboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1997-06-17 | — | — | US | claimed |
| EP-0188194-B1 | AMINOACRYLIC ACID DERIVATIVES | BAYER AG (DE) | 1990-07-04 | — | — | EP | claimed |
| CN-86100221-A | AMINOACRYLIC ACID DERIVATIVES | — | 1986-07-16 | — | — | CN | claimed |
| JP-2231476-A | — | — | None | — | — | JP | disclosed |
| JP-7196621-A | — | — | None | — | — | JP | disclosed |
| CN-113185505-B | Quinolone oxazolidinone compound and preparation method and application thereof | 中国农业大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-114222839-A | Antibacterial agent for high-pressure processing of fibers and high-pressure antibacterial processing method of fibers | 大和化学工业株式会社 | 2022-03-22 | — | — | CN | disclosed |
| CN-113185505-A | Quinolone oxazolidinone compound and preparation method and application thereof | 中国农业大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-111683930-A | Novel isoxazole compound or salt thereof | 日本欧爱特农业科技株式会社 | 2020-09-18 | — | — | CN | disclosed |
| CN-85101832-A | The method for preparing 7-(3-aryl-1-piperazinyl)-3-quinolone carboxylic acid and 7-(3-encircles ethyl-1-piperazinyl)-3-quinolone carboxylic acid | — | 1987-01-31 | — | — | CN | disclosed |
| CN-85101810-A | 7-amido-1-cyclopropyl-6,8-dihalo-1,4-dihydro-4-oxo-3-quinoline carboxylic acid's preparation method | — | 1987-01-17 | — | — | CN | disclosed |
| CN-86100221-A | AMINOACRYLIC ACID DERIVATIVES | — | 1986-07-16 | — | — | CN | disclosed |
| CN-86100221-A | AMINOACRYLIC ACID DERIVATIVES | — | 1986-07-16 | — | — | CN | disclosed |
| US-4404201-A | N-/ /ALKANOYLAMINOALKANOYLAMINO OR AMINOALKANOYL AMINO/-DIHYDRO-OXO-3-QUINOLINYLCARBONYL/- DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1983-09-13 | — | — | US | disclosed |
| US-4382089-A | Antibacterial amide compounds, compositions thereof and methods of using them | WARNER-LAMBERT COMPANY (US) | 1983-05-03 | — | — | US | disclosed |
| US-4374138-A | PENICILLINS | WARNER-LAMBERT COMPANY (US) | 1983-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030208069-A1 | Method for producing 8-methoxy-quinoline carboxylic acids | QARS1, QPCT, PAM | DAO 91/4885TSHR 4394/4885NAPRT 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.