Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 19/20 | 0.45 |
| ▸ | ITGB2 | P05107 | 18/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715248 | 1.00 | ITGAL (0.45) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL2388923 | 0.86 | ITGAL (0.61) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL13817298 | 0.76 | ITGB2 (0.75) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL5000918 | 0.76 | ITGB2 (0.75) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL12975639 | 0.73 | ITGAL (0.64) | ITGALITGB2ICAM1 | |
| SCHEMBL2390822 | 0.73 | ITGAL (0.63) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL12802530 | 0.72 | ITGAL (0.62) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL15375594 | 0.72 | ITGAL (0.61) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL10277854 | 0.72 | ITGAL (0.44) | ITGALITGB2ICAM1TMEM97 | |
| SCHEMBL15375595 | 0.71 | ITGAL (0.54) | ITGALITGB2ICAM1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225238-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZOÝ1,2- ¨IMIDAZOLE-3- CARBOXYLIC ACID AMIDES | Boehringer Ingelheim International GmbH (DE) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009070485-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-α]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-04 | — | — | WO | disclosed |