Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3805628 | 0.81 | FSCN1 (0.36) | SLC6A2SLC6A4CYP2D6KCNH2FSCN1 | |
| SCHEMBL6005672 | 0.74 | HDAC8 (0.45) | HDAC8HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3712560 | 0.71 | FSCN1 (0.37) | SLC6A2SLC6A4SLC6A3FSCN1 | |
| SCHEMBL6136395 | 0.70 | FSCN1 (0.53) | FSCN1 | |
| SCHEMBL11458388 | 0.70 | IDO1 (0.49) | HDAC8HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3711254 | 0.69 | FSCN1 (0.34) | SLC6A2SLC6A4FSCN1 | |
| SCHEMBL8591917 | 0.68 | IDO1 (0.47) | HDAC8HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL13941148 | 0.68 | IDO1 (0.47) | HDAC8HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL20606619 | 0.67 | HTT (0.44) | SLC6A2SLC6A4HDAC6SLC6A3 | |
| SCHEMBL4967508 | 0.66 | HTT (0.50) | SLC6A2SLC6A4EPHX2CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091164-A1 | INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE | EXELIXIS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |