Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712560 | 0.88 | FSCN1 (0.37) | FSCN1SLC6A2SLC6A4KMT2AMEN1 | |
| SCHEMBL3805628 | 0.79 | FSCN1 (0.36) | FSCN1SLC6A2SLC6A4NPC1RAB9A | |
| SCHEMBL3715485 | 0.69 | SLC6A2 (0.45) | FSCN1SLC6A2SLC6A4 | |
| SCHEMBL3711255 | 0.68 | UGCG (0.54) | ALDH1A1 | |
| SCHEMBL3712562 | 0.58 | UGCG (0.54) | ALDH1A1 | |
| SCHEMBL7227154 | 0.58 | FSCN1 (0.46) | FSCN1SLC6A2SLC6A4LMNAALDH1A1 | |
| SCHEMBL7636099 | 0.56 | HSD17B1 (0.37) | FSCN1KMT2AMEN1LMNANPC1 | |
| SCHEMBL6136395 | 0.56 | FSCN1 (0.53) | FSCN1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7570565 | 0.56 | ALDH1A1 (0.47) | FSCN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL31692229 | 0.56 | PDK2 (0.46) | FSCN1KMT2AMEN1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091164-A1 | INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE | EXELIXIS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |