Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.69 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.55 |
| ▸ | STS | P08842 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | TNKS | O95271 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30694898 | 1.00 | PPARG (0.69) | PPARGCYP11B1CYP11B2STSALOX15 | |
| SCHEMBL3660694 | 0.90 | PPARG (0.65) | PPARGCYP11B1CYP11B2STSALOX15 | |
| SCHEMBL3662892 | 0.89 | ALOX15 (0.68) | PPARGCYP11B1CYP11B2STSALOX15 | |
| SCHEMBL28050777 | 0.87 | ALOX15 (0.66) | PPARGCYP11B1CYP11B2STSALOX15 | |
| SCHEMBL3657376 | 0.87 | ALOX15 (0.66) | PPARGCYP11B1CYP11B2STSALOX15 | |
| SCHEMBL3654554 | 0.87 | ALOX15 (0.66) | PPARGCYP11B1CYP11B2STSALOX15 | |
| SCHEMBL16893235 | 0.87 | ALOX15 (0.66) | PPARGCYP11B1CYP11B2STSALOX15 | |
| SCHEMBL3660146 | 0.87 | ALOX15 (0.66) | PPARGCYP11B1CYP11B2STSALOX15 | |
| SCHEMBL21166318 | 0.87 | ALOX15 (0.66) | PPARGCYP11B1CYP11B2STSALOX15 | |
| SCHEMBL30876965 | 0.86 | PPARG (0.63) | PPARGCYP11B1CYP11B2MAOBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994079-A | Method for synthesizing chromone, 1-thiochromone and gamma-pyrone compounds | 中国科学院上海药物研究所 | 2024-11-22 | — | — | CN | disclosed |
| EP-3841211-A1 | METHODS FOR MANUFACTURING PLANT MESSENGER PACKS | Flagship Pioneering Innovations VI, LLC (US) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020041784-A1 | METHODS FOR MANUFACTURING PLANT MESSENGER PACKS | FLAGSHIP PIONEERING INNOVATIONS VI, LLC. (US) | 2020-02-27 | — | — | WO | disclosed |
| US-9844220-B2 | Synergistic fungicidal active substance combinations | FMC CORPORATION (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160150785-A1 | Synergistic Fungicidal Active Substance Combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-02 | — | — | US | disclosed |
| US-9288988-B2 | Synergistic fungicidal active substance combinations | FMC CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-9049867-B2 | Synergistic fungicidal active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-09 | — | — | US | disclosed |
| US-9006143-B2 | Synergistic fungicidal active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
| WO-2014079724-A1 | PESTICIDAL MIXTURES | BASF SE (DE) | 2014-05-30 | — | — | WO | disclosed |
| US-20130196981-A1 | Synergistic Fungicidal Active Substance Combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-01 | — | — | US | disclosed |
| WO-1997017347-A1 | COMPOUNDS DERIVED FROM OXAZOLIDIN-2-ONE AND PREPARATION AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-05-15 | — | — | WO | disclosed |
| EP-0441852-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1997-05-14 | — | — | EP | disclosed |
| US-5422358-A | Muscarinic receptor antagonists | PFIZER INC (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0441852-A1 | MUSCARINIC RECEPTOR ANTAGONISTS. | PFIZER LTD (GB) | 1991-08-21 | — | — | EP | disclosed |
| EP-0376358-A1 | Muscarinic receptor antagonists | PFIZER INC. (US) | 1990-07-04 | — | — | EP | disclosed |
| WO-1990005133-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1990-05-17 | — | — | WO | disclosed |
| EP-0144729-B1 | 11-Substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines, a process for their preparation and their use in medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-11-08 | — | — | EP | disclosed |
| US-4681879-A | 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-07-21 | — | — | US | disclosed |
| US-4608374-A | 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-08-26 | — | — | US | disclosed |
| EP-0144729-A1 | 11-Substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines, a process for their preparation and their use in medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160150785-A1 | Synergistic Fungicidal Active Substance Combinations | CYP1A2, CAT, CYP51A1 | PPARG 2611/4885CYP11B1 362/4885CYP11B2 203/4885 |
| US-20130196981-A1 | Synergistic Fungicidal Active Substance Combinations | CYP51A1, CYP1A2, CYP4X1 | PPARG 2802/4885CYP11B1 278/4885CYP11B2 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.