SCHEMBL3715560

SCHEMBL3715560

COn1c(NCCc2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)COc1ccc(Cl)cc1)CC2

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRLHR P49683 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3720145 0.94 PRLHR (0.71) PRLHR
SCHEMBL3715452 0.91 PRLHR (0.78) PRLHR
Hydrochloric Acid SCHEMBL3723921 0.88 PRLHR (0.64) PRLHR
Hydrochloric Acid SCHEMBL3720710 0.87 PRLHR (0.85) PRLHR
SCHEMBL3716367 0.86 PRLHR (0.59) PRLHR
SCHEMBL17319398 0.85 PRLHR (1.00) PRLHR
SCHEMBL435811 0.85 PRLHR (1.00) PRLHR
SCHEMBL3723098 0.83 PRLHR (0.70) PRLHR
SCHEMBL3716959 0.83 PRLHR (0.75) PRLHR
SCHEMBL3719972 0.83 PRLHR (0.74) PRLHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010137738-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF STRESS-RELATED CONDITIONS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2010-12-02 WO disclosed