SCHEMBL3719972

SCHEMBL3719972

COc1cc(Cl)ccc1C(=O)N1CCc2nc(NCCc3ccc(C(F)(F)F)cc3)n(OC)c(=O)c2C1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRLHR P49683 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3723098 0.92 PRLHR (0.70) PRLHR
Hydrochloric Acid SCHEMBL3720710 0.88 PRLHR (0.85) PRLHR
SCHEMBL3719887 0.86 PRLHR (0.76) PRLHR
SCHEMBL3716887 0.85 PRLHR (0.73) PRLHR
SCHEMBL3715452 0.85 PRLHR (0.78) PRLHR
SCHEMBL436928 0.85 PRLHR (1.00) PRLHR
SCHEMBL450455 0.85 PRLHR (1.00) PRLHR
SCHEMBL3716959 0.84 PRLHR (0.75) PRLHR
SCHEMBL3713146 0.83 PRLHR (0.72) PRLHR
SCHEMBL3715560 0.83 PRLHR (0.74) PRLHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010137738-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF STRESS-RELATED CONDITIONS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2010-12-02 WO disclosed