Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | USP47 | Q96K76 | 5/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | USP10 | Q14694 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716798 | 0.83 | USP7 (0.59) | USP7MAPTALDH1A1TDP1KDM4E | |
| SCHEMBL3715754 | 0.81 | USP7 (0.72) | USP7MAPTALDH1A1TDP1KDM4E | |
| SCHEMBL3723562 | 0.81 | USP47 (0.43) | USP7MAPTALDH1A1TDP1KDM4E | |
| SCHEMBL3715105 | 0.81 | USP7 (0.45) | USP7MAPTALDH1A1TDP1KDM4E | |
| SCHEMBL3712957 | 0.77 | USP7 (0.58) | USP7USP47 | |
| SCHEMBL3720858 | 0.76 | HTT (0.39) | USP7MAPTALDH1A1TDP1KDM4E | |
| SCHEMBL3714784 | 0.76 | USP47 (0.48) | USP7MAPTALDH1A1TDP1KDM4E | |
| SCHEMBL3715157 | 0.75 | USP7 (0.60) | USP7MAPTALDH1A1TDP1KDM4E | |
| SCHEMBL3719652 | 0.75 | USP7 (0.60) | USP7MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL3717157 | 0.75 | USP7 (0.69) | USP7MAPTTDP1NPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | claimed |