Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | UTRN | P46939 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812296 | 0.78 | CYP1A2 (0.51) | CYP1A2AHRUTRNHDAC6RAB9A | |
| SCHEMBL3812306 | 0.78 | CYP1A2 (0.51) | CYP1A2AHRUTRNHDAC6RAB9A | |
| SCHEMBL3812302 | 0.78 | CYP1A2 (0.51) | CYP1A2AHRUTRNHDAC6RAB9A | |
| SCHEMBL3717356 | 0.77 | CYP1A2 (0.50) | CYP1A2AHRUTRNHDAC6RAB9A | |
| SCHEMBL12324816 | 0.75 | MAPT (0.65) | CYP1A2AHRUTRNHDAC6RAB9A | |
| SCHEMBL2243039 | 0.75 | UTRN (0.77) | CYP1A2AHRUTRNHDAC6RAB9A | |
| SCHEMBL2245790 | 0.73 | UTRN (0.77) | CYP1A2AHRUTRNHDAC6RAB9A | |
| SCHEMBL4363580 | 0.72 | UTRN (0.58) | CYP1A2AHRUTRNHDAC6RAB9A | |
| SCHEMBL4363584 | 0.72 | UTRN (0.58) | CYP1A2AHRUTRNHDAC6RAB9A | |
| SCHEMBL3717358 | 0.71 | KMT2A (0.53) | CYP1A2AHRUTRNHDAC6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010112092-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULARY DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-10-07 | — | — | WO | claimed |