Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 7/20 | 0.37 |
| ▸ | USP47 | Q96K76 | 4/20 | 0.36 |
| ▸ | USP10 | Q14694 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716051 | 0.88 | USP7 (0.42) | USP7USP47USP10PADI4 | |
| SCHEMBL3715157 | 0.79 | USP7 (0.60) | USP7USP47USP10KDM4EALDH1A1 | |
| SCHEMBL3712957 | 0.79 | USP7 (0.58) | USP7USP47PADI4 | |
| SCHEMBL3716279 | 0.78 | USP7 (0.59) | USP7USP47 | |
| SCHEMBL3720903 | 0.75 | USP7 (0.43) | USP7USP47KDM4EALDH1A1MAPT | |
| SCHEMBL3712491 | 0.75 | USP7 (0.56) | USP7USP47PADI4 | |
| SCHEMBL3717382 | 0.75 | MGAM (0.36) | USP7USP47USP10KDM4EALDH1A1 | |
| SCHEMBL3719648 | 0.74 | USP7 (0.43) | USP7USP47KDM4EALDH1A1GLA | |
| SCHEMBL27154247 | 0.74 | PDE7A (0.44) | USP7USP47KDM4EALDH1A1GLA | |
| SCHEMBL3715750 | 0.74 | USP7 (0.57) | USP7USP47TDP1PADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | claimed |
| WO-2010114881-A1 | ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS | PROGENRA INC. (US) | 2010-10-07 | — | — | WO | disclosed |